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Analysis of 3D CT image data aimed at detection and classification of specific tissue structures
Šalplachta, Jakub ; Malínský, Miloš (referee) ; Jan, Jiří (advisor)
This thesis deals with the segmentation and classification of paraspinal muscle and subcutaneous adipose tissue in 3D CT image data in order to use them subsequently as internal calibration phantoms to measure bone mineral density of a vertebrae. Chosen methods were tested and afterwards evaluated in terms of correctness of the classification and total functionality for subsequent BMD value calculation. Algorithms were tested in programming environment Matlab® on created patient database which contains lumbar spines of twelve patients. Following sections of this thesis contain theoretical research of the issue of measuring bone mineral density, segmentation and classification methods and description of practical part of this work.
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Methods of measurement of bone density
Konvalinka, Jan ; Valášek, Jiří (referee) ; Marcián, Petr (advisor)
This bachelor's thesis focuses on methods for measuring bone density and consequences of changes in bone density on biomechanical properties of bone tissue. In first part are described methods of bone densitometry, especially radiological methods, which are currently most widely used. Second part focuses on measuring bone density from CT images (hog femur bone, healthy and damaged human femur bone and lumbar vertebra) using software ROI Analysis. Third part discusses influence of changes in bone density on strain-stress quantities of trabecular bone. For the assessment was created 2D computational model of hip using FEM.
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Analysis of 3D CT image data aimed at segmentation of bone elements and other specific tissue types
Kodym, Oldřich ; Herout, Adam (referee) ; Jan, Jiří (advisor)
The goal of this thesis is to get acquainted with methods of determining bone mineral density from appropriate tissue types in diagnostic CT data and possibly modifying or extending them in order to make the bone quality diagnosis more reliable. The thesis begins by introducing the issue of determining bone quality. Next, a method that takes cortical bone deformations into account as well as bone mineral density is introduced. Accuracy assessment based on opinion of a medical expert suggests positive outcome of future objective accuracy assessment utilizing so far unavailable base of calibrated CT data, that is needed before deployment into clinical practice. If the accuracy of the suggested method is confirmed this way, this work provides a so far absent tool for fully automatic preventive diagnostics of osteoporosis.
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Estimation of bone mineral density of cancellous vertebral bone in multi-energy CT data
Líška, Martin ; Jakubíček, Roman (referee) ; Chmelík, Jiří (advisor)
The principle of the BMD estimation method presented in this thesis consists in the tomographic scanning of the axial skeleton by a CT system with two different energies. The BMD estimation method was applied to acquisitions scanned by CT system IQon Spectral CT (Philips) on seven patients, two men and five women, in the lumbo-sacral region. For the functionality of the method, it is necessary to know the standardized amounts of selected elemental components contained in a given tissue, specifically in the cancellous bone of the vertebra. In the first part, the thesis deals with the theoretical part of solving the estimation of BMD from dual-energy CT data, two equations with several unknowns and their modification. The practical part deals with the program solution of the method of calculating the estimation of bone minerals in dual-energy CT data. The outputs of the presented BMD estimation method were processed and statistically compared with the other two phantom-less BMD estimation methods. The functionality of the method and statistical processing were solved in MATLAB and STATISTICA softwares.
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The Use of Vibration in Sports and Health Care
Koutná, Martina ; Stackeová, Daniela (advisor) ; Malá, Jitka (referee)
Title: The Use of Vibration in Sports and Health Care Objectives: The aim of this study is to determine whole-body vibration training as potential training method in sport and health area. The usage of vibration training should increase strength, bone mineral density, and balance. Methods: This diploma thesis is solely theoretical. It is based on review of available literary sources, clinical trials accessible through electronic databases of medical and sports, and library catalogs. The resources from sport, physiology, biomechanics, and various medical disciplines (osteology, physiotherapy, kinesiology) were used also. Results: The research concluded that the usage of whole-body vibration of an appropriate frequency or acceleration respectively could represent an alternative or a supplement to conventional training in order to increase muscle strength and bone mineral density or improve balance and mobility of elderly. The selection of right vibration parameters could support ordinary physical therapy of some neurological disorders. Keywords: vibration, whole-body vibration training, muscle strength, balance, bone mineral density, neurological disorders, physical therapy
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The influence of whole-body electromyostimulation on muscle strength and body composition in healthy individuals
Kamarýtová, Magdaléna ; Coufalová, Klára (advisor) ; Hráský, Pavel (referee)
Title: The influence of whole-body electromyostimulation on muscle strength and body composition in healthy individuals Objectives: The aim of the diploma thesis is to collect and give comprehensive theoretical information concerning the whole body electromyostimulation topic. Furthermore, find out what the effect of the whole body electromyostimulation method on body weight, fat-free mass, body fat and other parameters of body composition. The aim of this work is to verify whether it is possible to achieve changes in bone mineral density values by means of the WB-EMS method or to increase maximal isometric muscle strength in healthy individuals. Methods: The diploma thesis is an intragroup experiment. The method of qualitative research was used for data collection. Bioelectric impedance analysis was used to evaluate body composition. DXA (Dual Energy X-Ray Absorptiometry) was used to assess bone mineral density and body composition, and isometric muscle strength was evaluated using isometric dynamometry. The research group consisted of 10 young and healthy probands (average age 23.9 years). Probands completed 10 exercise units using the whole body electromyostimulation method. The frequency of exercise was once a week. Results: We have found that after ten weeks of using the whole-body...
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Impact of glucocorticoid treatment on musculosceletal system of pediatric patients with acute lymphoblastic leukemia.
Petráčková, Karolína ; Jevič, Filip (advisor) ; Šrámková, Lucie (referee)
This bachelor thesis aims to provide a general overview of complications of musculoskeletal system in pediatric patients diagnosed with acute lymphoblastic leukemia (ALL) undergoing chemotherapy treatment involving high cumulative doses of glucocorticoids. Musculoskeletal complications include steroid myopathy, osteonecrosis and reduced bone mineral density. The first part describes their basic pathophysiological mechanisms and the risk factors of their origin. The second part presents the current possibilities of muscle strength assessment and available exercise programs. Furthermore, diagnosis of osteonecrosis and bone mineral density are presented together with current possibilities of therapeutic intervention. The thesis also covers characteristics of muscle strength measuring methods and exercise programs along with presentation of the results of individual studies. In the discussion part, there are broken down the limits, advantages and disadvantages of using the muscle strength measuring methods and exercise programs in clinical practice.
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Use of vibration in sports and health care
Koutná, Martina ; Malá, Jitka (advisor) ; Pavlů, Dagmar (referee)
Title: The Use of Vibration in Sports and Health Care Objectives: The aim of this study is to confirm or refute established hypotheses. Hypotheses: 1. The use of vibration loading improves muscle strength. 2. The use of vibration loading improves bone mineral density. 3. The use of vibration loading can influence balance. Methods: This diploma thesis is elaborated as search form. It is based on exploration of available literary sources, clinical trials accessible through electronic databases of medical and sports, and library catalogs. The resources from sport, physiology, biomechanics, and various medical disciplines (osteology, physiotherapy, kinesiology) were used also. Results: Due to retrieval process of whole body vibration training it was found out that this method can improve muscle strength, bone mineral density, balance and mobility. The effect depends on chosen parameters of whole-body vibrations. Under certain conditions whole-body vibration training could represent an alternative or a supplement to conventional training in order to increase muscle strength and bone mineral density or improve balance and mobility of elderly. The selection of right vibration parameters could support ordinary physical therapy of some neurological disorders. Keywords: vibration, whole-body vibration...
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Effect of celiac disease on growth and bone density.
Ondráčková, Markéta ; Zemková, Daniela (advisor) ; Tůma, Jan (referee)
Celiac disease is a chronic autoimmune disease of the small intestine caused by intolerance to gluten. The disease is characterized by impairment of intestinal mucosa, it is associated with malabsorption and maldigestion. The main symptoms are stomach pain, diarrhea, anemia, failure to thrive. Recently, the number of patients with atypical symptoms and a completely asymptomatic form of the disease increases. Prevalence of the disease in Europe is 1 %. The aim of this paper is to describe how celiac disease affects the status of bone tissue and what is its impact on growth in children.
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